enterokinase是什么意思，enterokinase翻译

enterokinase是什么意思，enterokinase翻译

Enterokinase: An Enzyme with Multiple Roles in the Body

Enterokinase, also known as enterokinase EC 3.4.23.4, is an enzyme that plays a crucial role in the digestion and absorption of nutrients in the small intestine. It is produced and secreted by the enterocytes, which are the cells that line the epithelial layer of the small intestine. This enzyme is involved in the activation of pancreatic trypsinogen, a zymogen that is secreted by the pancreas.

The production and secretion of enterokinase is regulated by various factors, including the presence of nutrients in the small intestine. When nutrients such as fats, proteins, and carbohydrates are present, enterokinase is released into the lumen of the small intestine. This enzyme is essential for the digestion and absorption of these nutrients by activating pancreatic trypsinogen to trypsin, which is a potent digestive enzyme.

Once enterokinase is released into the small intestine, it binds to the trypsinogen and cleaves a specific peptide bond, resulting in the activation of trypsin. This activation is crucial for the subsequent activation of other pancreatic zymogens, such as chymotrypsinogens and amylase, which are also essential for the digestion of nutrients in the small intestine.

In addition to its role in digestion, enterokinase is also involved in the regulation of blood pressure and fluid balance. It does this by activating a hormone called renin, which is produced and secreted by the kidneys. Renin is an essential component of the renin